ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Sorbs1

Full Name:

sorbin and SH3 domain containing 1

Alias:

2310065E01Rik|9530001P15Rik|CAP|SH3P12|Sh3d5|mKIAA1296

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 C3|19 36.5 cM

Physical Location:

40366529-40588301 on NC_000085.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10580 Symbol (Name): SORBS1 (sorbin and SH3 domain containing 1)

Ortholog Status:

The human GeneID 10580 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0001725	stress fiber	Cellular Component	IDA (9461600)
GO:0016020	membrane	Cellular Component	IEA
GO:0030054	cell junction	Cellular Component	IEA
GO:0045121	membrane raft	Cellular Component	IDA (11001060)
GO:0005924	cell-substrate adherens junction	Cellular Component	IDA (10085297)
GO:0005913	cell-cell adherens junction	Cellular Component	IDA (10085297)
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (9447983\|9461600\|10085297)
GO:0005158	insulin receptor binding	Molecular Function	IDA (9447983)
GO:0019901	protein kinase binding	Molecular Function	IDA (9461600)
GO:0043149	stress fiber formation	Biological Process	IDA (9461600)
GO:0015758	glucose transport	Biological Process	IDA (11001060)
GO:0008286	insulin receptor signaling pathway	Biological Process	IDA (9447983)
GO:0006810	transport	Biological Process	IEA
GO:0048041	focal adhesion formation	Biological Process	IDA (9461600)