ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

EPHB1

Full Name:

EPH receptor B1

Alias:

ELK|EPHT2|FLJ37986|Hek6|NET

Organism:

Homo sapiens (Human)

Chromosome:

3

Genetic Location:

3q21-q23

Physical Location:

135996949-136461998 on NC_000003.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID	No. of Publications	Phenotype
EPHB1	1	Alcoholism

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004441.3	NP_004432.1	NC_000003.10 range: 135996949..136461998

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (8666391)
GO:0005886	plasma membrane	Cellular Component	TAS (8666391)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (8798570)
GO:0005003	ephrin receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	TAS (8666391)
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Biological Process	IEA
GO:0007399	nervous system development	Biological Process	TAS (8666391)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000154928

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: