ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Slc2a1

Full Name:

solute carrier family 2 (facilitated glucose transporter), member 1

Alias:

Glut-1|Glut1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D2.1|4 52.0 cM

Physical Location:

118781372-118809931 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6513 Symbol (Name): SLC2A1 (solute carrier family 2 (facilitated glucose transporter), member 1)

Ortholog Status:

The human GeneID 6513 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		M22998
Fold Change:		1.6, 1.6, 1.5, 1.5
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011400.3	NP_035530.2	NC_000070.5 range: 118781372..118809931

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016323	basolateral plasma membrane	Cellular Component	IDA (15975910)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	IDA (11172003\|14562105\|15800058)
GO:0005737	cytoplasm	Cellular Component	IDA (15800058)
GO:0005622	intracellular	Cellular Component	IDA (11172003)
GO:0005515	protein binding	Molecular Function	IPI (15975910)
GO:0005355	glucose transmembrane transporter activity	Molecular Function	IEA
GO:0005351	sugar:hydrogen symporter activity	Molecular Function	IEA
GO:0005215	transporter activity	Molecular Function	IEA
GO:0006810	transport	Biological Process	IEA
GO:0008643	carbohydrate transport	Biological Process	IEA