ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Sox15

Full Name:

SRY-box containing gene 15

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B3|11 39.0 cM

Physical Location:

69468874-69470122 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6665 Symbol (Name): SOX15 (SRY (sex determining region Y)-box 15)

Ortholog Status:

The human GeneID 6665 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore4	Alcohol-induced Loss of Righting Reflex	11		36-42 (cM)	6.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009235.1	NP_033261.1	NC_000077.5 range: 69468874..69470122

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (10821863\|15367664\|15863505)
GO:0000785	chromatin	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IDA (12915303)
GO:0003677	DNA binding	Molecular Function	IDA (10821863)
GO:0003677	DNA binding	Molecular Function	IGI (15863505)
GO:0003682	chromatin binding	Molecular Function	IDA (15863505)
GO:0005515	protein binding	Molecular Function	IPI (15863505\|16759287)
GO:0030528	transcription regulator activity	Molecular Function	IGI (16759287)
GO:0030528	transcription regulator activity	Molecular Function	IDA (16759287)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (16759287)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (15863505\|16759287)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (10821863)
GO:0045843	negative regulation of striated muscle development	Biological Process	IDA (10821863)
GO:0043403	skeletal muscle regeneration	Biological Process	IMP (15367664)
GO:0030154	cell differentiation	Biological Process	IGI (16759287)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0048627	myoblast development	Biological Process	IMP (15367664)