ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

2073

Symbol:

ERCC5

Full Name:

excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))

Alias:

COFS3|ERCM2|UVDR|XPG|XPGC

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

13q22|13q33

Physical Location:

102296174-102326345 on NC_000013.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ERCC5

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000123.2	NP_000114.2	NC_000013.9 range: 102296174..102326345

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005675	holo TFIIH complex	Cellular Component	IDA (11259578)
GO:0005654	nucleoplasm	Cellular Component	EXP (10214908\|11313499)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IDA (8710877)
GO:0042803	protein homodimerization activity	Molecular Function	IPI (10026181)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0000405	bubble DNA binding	Molecular Function	IDA (16246722)
GO:0004527	exonuclease activity	Molecular Function	IEA
GO:0004520	endodeoxyribonuclease activity	Molecular Function	IDA (8090225\|12644470)
GO:0004519	endonuclease activity	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0047485	protein N-terminus binding	Molecular Function	IPI (8652557)
GO:0003690	double-stranded DNA binding	Molecular Function	IDA (8090225\|12644470)
GO:0003697	single-stranded DNA binding	Molecular Function	IDA (12644470)
GO:0004518	nuclease activity	Molecular Function	IEA
GO:0003697	single-stranded DNA binding	Molecular Function	IEA
GO:0043066	negative regulation of apoptosis	Biological Process	IMP (16167068)
GO:0000718	nucleotide-excision repair, DNA damage removal	Biological Process	EXP (10583946)
GO:0010225	response to UV-C	Biological Process	IMP (17208056)
GO:0009650	UV protection	Biological Process	IGI (7510366)
GO:0007605	sensory perception of sound	Biological Process	IEA
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	Biological Process	IMP (7657672)
GO:0006289	nucleotide-excision repair	Biological Process	IEA
GO:0006283	transcription-coupled nucleotide-excision repair	Biological Process	IMP (16246722)
GO:0006281	DNA repair	Biological Process	IEA
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	Biological Process	IDA (8090225)