ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

2074

Symbol:

ERCC6

Full Name:

excision repair cross-complementing rodent repair deficiency, complementation group 6

Alias:

ARMD5|CKN2|COFS|COFS1|CSB|RAD26

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

10q11.23

Physical Location:

50336714-50417077 on NC_000010.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ERCC6

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000124.2	NP_000115.1	NC_000010.9 range: 50336714..50417077, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005654	nucleoplasm	Cellular Component	EXP (11313499)
GO:0005634	nucleus	Cellular Component	IDA (12560492)
GO:0005625	soluble fraction	Cellular Component	IDA (16916636)
GO:0005654	nucleoplasm	Cellular Component	IDA (16107709)
GO:0008023	transcription elongation factor complex	Cellular Component	IDA (9326587)
GO:0005730	nucleolus	Cellular Component	IDA (16107709)
GO:0047485	protein N-terminus binding	Molecular Function	IPI (7664335)
GO:0008022	protein C-terminus binding	Molecular Function	IPI (16246722)
GO:0008094	DNA-dependent ATPase activity	Molecular Function	IDA (8999876\|12560492\|16107709)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0032403	protein complex binding	Molecular Function	IDA (16916636)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0003682	chromatin binding	Molecular Function	IDA (16916636)
GO:0003678	DNA helicase activity	Molecular Function	IDA (8999876)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IDA (8999876\|12560492\|16107709)
GO:0004386	helicase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IDA (12560492\|16107709)
GO:0003711	transcription elongation regulator activity	Molecular Function	IDA (9326587)
GO:0032786	positive regulation of RNA elongation	Biological Process	IDA (9326587)
GO:0009411	response to UV	Biological Process	IDA (16916636)
GO:0007605	sensory perception of sound	Biological Process	IEA
GO:0006979	response to oxidative stress	Biological Process	IDA (16107709)
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	NAS (7664335)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0006284	base-excision repair	Biological Process	IMP (9973627)
GO:0006283	transcription-coupled nucleotide-excision repair	Biological Process	IMP (10564257\|16916636)