ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Aldh4a1

Full Name:

aldehyde dehydrogenase 4 family, member A1

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D3|4 66.1 cM

Physical Location:

139178924-139205601 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 8659 Symbol (Name): ALDH4A1 (aldehyde dehydrogenase 4 family, member A1)

Ortholog Status:

The human GeneID 8659 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_175438.3	NP_780647.2	NC_000070.5 range: 139178924..139205601

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0005759	mitochondrial matrix	Cellular Component	RCA (12466851)
GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity	Molecular Function	RCA (12466851)
GO:0009055	electron carrier activity	Molecular Function	RCA (12466851)
GO:0016491	oxidoreductase activity	Molecular Function	RCA (12466851)
GO:0004029	aldehyde dehydrogenase (NAD) activity	Molecular Function	RCA (12466851)
GO:0006560	proline metabolic process	Biological Process	RCA (12466851)
GO:0006562	proline catabolic process	Biological Process	RCA (12466851)
GO:0008152	metabolic process	Biological Process	RCA (12466851)
GO:0006561	proline biosynthetic process	Biological Process	IEA