ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Chrm5

Full Name:

cholinergic receptor, muscarinic 5

Alias:

M5R|m5

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 E3

Physical Location:

112319327-112320925 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1133 Symbol (Name): CHRM5 (cholinergic receptor, muscarinic 5)

Ortholog Status:

The human GeneID 1133 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_205783.1	NP_991352.1	NC_000068.6 range: 112319327..112320925, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045211	postsynaptic membrane	Cellular Component	IEA
GO:0045202	synapse	Cellular Component	IEA
GO:0030054	cell junction	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0001584	rhodopsin-like receptor activity	Molecular Function	IEA
GO:0004981	muscarinic acetylcholine receptor activity	Molecular Function	IEA
GO:0004930	G-protein coupled receptor activity	Molecular Function	IEA
GO:0004891	glycine-inhibited chloride channel activity	Molecular Function	TAS (11756520)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0007165	signal transduction	Biological Process	IEA
GO:0015872	dopamine transport	Biological Process	IDA (11756520)
GO:0019226	transmission of nerve impulse	Biological Process	IDA (11756520)
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IEA