ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tcf7l2

Full Name:

transcription factor 7-like 2, T-cell specific, HMG-box

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 D2|19 53.0 cM

Physical Location:

55816758-56007731 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6934 Symbol (Name): TCF7L2 (transcription factor 7-like 2 (T-cell specific, HMG-box))

Ortholog Status:

The human GeneID 6934 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009333.2	NP_033359.2	NC_000085.5 range: 55816758..56007731

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (15778706)
GO:0005667	transcription factor complex	Cellular Component	IDA (12861022)
GO:0005829	cytosol	Cellular Component	IDA (15578569)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0008013	beta-catenin binding	Molecular Function	IPI (9488439\|12874278)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA (12861022)
GO:0006350	transcription	Biological Process	IEA
GO:0016055	Wnt receptor signaling pathway	Biological Process	IDA (9488439)
GO:0021915	neural tube development	Biological Process	IGI (15057272)
GO:0030538	embryonic genitalia morphogenesis	Biological Process	IGI (15057272)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (15778706)
GO:0048557	embryonic digestive tract morphogenesis	Biological Process	IGI (15057272)
GO:0048619	embryonic hindgut morphogenesis	Biological Process	IGI (15057272)