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Gene Information
Gene ID:2162
Symbol:F13A1
Full Name:coagulation factor XIII, A1 polypeptide
Alias:F13A
Organism:Homo sapiens (Human)
Chromosome:6
Genetic Location:6p25.3-p24.3
Physical Location:6089309-6265922 on NC_000006.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D6S1574  5957132
Region:3957132-7957132
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
MarkerLODP valueLocation (bp)
D6S309  8169921
Region:6169921-10169921
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000129.3NP_000120.2NC_000006.10 range: 6089309..6265922, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005576extracellular regionCellular ComponentEXP (2866798)
GO:0005576extracellular regionCellular ComponentTAS (2877457)
GO:0016740transferase activityMolecular FunctionIEA
GO:0008415acyltransferase activityMolecular FunctionIEA
GO:0003810protein-glutamine gamma-glutamyltransferase activityMolecular FunctionIEA
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0003810protein-glutamine gamma-glutamyltransferase activityMolecular FunctionTAS (2877456)
GO:0007596blood coagulationBiological ProcessTAS (10801785)
GO:0018149peptide cross-linkingBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:2162
HGNC:3531
Ensembl:ENSG00000124491
MIM:134570
HPRD:00604
HuGE Navigator:2162
dbSNP:F13A1
GeneCard:F13A1
AceView:F13A1