ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tdgf1

Full Name:

teratocarcinoma-derived growth factor

Alias:

CR1|cripto

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 F3|9 60.0 cM

Physical Location:

110842111-110848661 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6997 Symbol (Name): TDGF1 (teratocarcinoma-derived growth factor 1)

Ortholog Status:

The human GeneID 6997 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact2	Alcohol Stimulated Activity	9	61	51-71 (cM)	3.6	4.30E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011562.2	NP_035692.2	NC_000075.5 range: 110842111..110848661, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	IDA (10640699)
GO:0031225	anchored to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0019897	extrinsic to plasma membrane	Cellular Component	IDA (10640699\|11992720)
GO:0008083	growth factor activity	Molecular Function	ISS (8006041)
GO:0000187	activation of MAPK activity	Biological Process	ISS (9013573)
GO:0030334	regulation of cell migration	Biological Process	IMP (9876177)
GO:0030335	positive regulation of cell migration	Biological Process	IDA (11133982)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (17568773)
GO:0010002	cardioblast differentiation	Biological Process	IMP (9876177)
GO:0008595	determination of anterior/posterior axis, embryo	Biological Process	IMP (9790191)
GO:0008284	positive regulation of cell proliferation	Biological Process	ISS (8006041)
GO:0007507	heart development	Biological Process	IDA (9576836)
GO:0007173	epidermal growth factor receptor signaling pathway	Biological Process	ISS (8006041)
GO:0001954	positive regulation of cell-matrix adhesion	Biological Process	IMP (9876177)
GO:0001763	morphogenesis of a branching structure	Biological Process	IDA (11133982)
GO:0001701	in utero embryonic development	Biological Process	IMP (9876177)
GO:0001570	vasculogenesis	Biological Process	IMP (9876177)
GO:0048146	positive regulation of fibroblast proliferation	Biological Process	IMP (9876177)