ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tlx1

Full Name:

T-cell leukemia, homeobox 1

Alias:

Hox-11|Hox11

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 C3|19 43.0 cM

Physical Location:

45225204-45231432 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3195 Symbol (Name): TLX1 (T-cell leukemia homeobox 1)

Ortholog Status:

The human GeneID 3195 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_021901.2	NP_068701.1	NC_000085.5 range: 45225204..45231432

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0046982	protein heterodimerization activity	Molecular Function	IPI (15944191)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0048536	spleen development	Biological Process	IMP (11356032)
GO:0048536	spleen development	Biological Process	IGI (15944191)
GO:0048535	lymph node development	Biological Process	TAS (10687308)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (15944191)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0045165	cell fate commitment	Biological Process	IMP (11356032)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0030182	neuron differentiation	Biological Process	IMP (12023301)
GO:0009987	cellular process	Biological Process	RCA (12466851)
GO:0008284	positive regulation of cell proliferation	Biological Process	IMP (15944191)
GO:0007417	central nervous system development	Biological Process	IMP (12023301)
GO:0048645	organ formation	Biological Process	IMP (11356032)