ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tnfrsf1b

Full Name:

tumor necrosis factor receptor superfamily, member 1b

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 E1|4 75.5 cM

Physical Location:

144802270-144836772 on NC_000070.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7133 Symbol (Name): TNFRSF1B (tumor necrosis factor receptor superfamily, member 1B)

Ortholog Status:

The human GeneID 7133 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011610.3	NP_035740.2	NC_000070.5 range: 144802270..144836772, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IDA (10747083)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (10747083)
GO:0050728	negative regulation of inflammatory response	Biological Process	IMP (11588035)
GO:0008283	cell proliferation	Biological Process	TAS (7990930)
GO:0008219	cell death	Biological Process	IMP (7990930)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	IMP (9551933)
GO:0006954	inflammatory response	Biological Process	IMP (9551933)
GO:0050779	RNA destabilization	Biological Process	IMP (11588035)