ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tnfsf11

Full Name:

tumor necrosis factor (ligand) superfamily, member 11

Alias:

Ly109l|ODF|OPG|OPGL|RANKL|Trance

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D3|14 45.0 cM

Physical Location:

78677252-78707849 on NC_000080.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 8600 Symbol (Name): TNFSF11 (tumor necrosis factor (ligand) superfamily, member 11)

Ortholog Status:

The human GeneID 8600 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws5/Alcw7	Chronic Alcohol Withdrawal	14		24-48 (cM)	4.2	6.00E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011613.3	NP_035743.2	NC_000080.5 range: 78677252..78707849, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (11859102)
GO:0005164	tumor necrosis factor receptor binding	Molecular Function	IEA
GO:0005125	cytokine activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0045453	bone resorption	Biological Process	IDA (12490655)
GO:0045670	regulation of osteoclast differentiation	Biological Process	IDA (12490655)
GO:0045672	positive regulation of osteoclast differentiation	Biological Process	IDA (15657444\|15724149)
GO:0045672	positive regulation of osteoclast differentiation	Biological Process	IGI (17053831)
GO:0048535	lymph node development	Biological Process	TAS (10687308)
GO:0030316	osteoclast differentiation	Biological Process	IGI (15485831)
GO:0030316	osteoclast differentiation	Biological Process	IDA (14662855)
GO:0030154	cell differentiation	Biological Process	IEA
GO:0001503	ossification	Biological Process	IMP (9950424)
GO:0009887	organ morphogenesis	Biological Process	IMP (9950424)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006955	immune response	Biological Process	IEA
GO:0051260	protein homooligomerization	Biological Process	IDA (11859102)