ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Dedd

Full Name:

death effector domain-containing

Alias:

CASP8IP1|DEFT|Dedpro1|FLDED1|KE05

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H2|1 90.0 cM

Physical Location:

173259641-173271745 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9191 Symbol (Name): DEDD (death effector domain containing)

Ortholog Status:

The human GeneID 9191 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw1	Acute Alcohol Withdrawal	1	96	172.3-176.5 (Mb)	5.6	3.00E-07	Significant	PARC
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011615.3	NP_035745.3	NC_000067.5 range: 173259641..173271745

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005730	nucleolus	Cellular Component	IDA (9774341)
GO:0005737	cytoplasm	Cellular Component	IDA (9774341)
GO:0003677	DNA binding	Molecular Function	IDA (9774341)
GO:0005515	protein binding	Molecular Function	IEA
GO:0016481	negative regulation of transcription	Biological Process	IDA (9774341)
GO:0006917	induction of apoptosis	Biological Process	IDA (9774341)
GO:0006915	apoptosis	Biological Process	RCA (12819136)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0042981	regulation of apoptosis	Biological Process	RCA (12819136)