ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

22062

Symbol:

Trp73

Full Name:

transformation related protein 73

Alias:

p73

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 E2|4 82.0 cM

Physical Location:

153432952-153514316 on NC_000070.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7161 Symbol (Name): TP73 (tumor protein p73)

Ortholog Status:

The human GeneID 7161 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011642.3	NP_035772.2	NC_000070.5 range: 153432952..153514316, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (14555234\|15483136\|15525772)
GO:0005515	protein binding	Molecular Function	ISS (15678106)
GO:0005515	protein binding	Molecular Function	TAS (14555234)
GO:0005515	protein binding	Molecular Function	IPI (15483136)
GO:0003700	transcription factor activity	Molecular Function	ISS (15678106)
GO:0003700	transcription factor activity	Molecular Function	IDA (16044147)
GO:0003677	DNA binding	Molecular Function	IDA (16363065)
GO:0002039	p53 binding	Molecular Function	IPI (10894779)
GO:0043524	negative regulation of neuron apoptosis	Biological Process	IDA (10894779\|12427836)
GO:0043523	regulation of neuron apoptosis	Biological Process	IGI (15483136)
GO:0043508	negative regulation of JNK activity	Biological Process	IDA (15483136)
GO:0001836	release of cytochrome c from mitochondria	Biological Process	IDA (15483136)
GO:0043524	negative regulation of neuron apoptosis	Biological Process	IMP (10894779\|12427836\|15483136)
GO:0045793	positive regulation of cell size	Biological Process	IMP (12427836\|15483136)
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA (16044147)
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	ISS (15678106)
GO:0048546	digestive tract morphogenesis	Biological Process	IMP (10716451)
GO:0043066	negative regulation of apoptosis	Biological Process	IDA (15983387)
GO:0042981	regulation of apoptosis	Biological Process	TAS (14555234)
GO:0033326	cerebrospinal fluid secretion	Biological Process	IMP (10716451)
GO:0006915	apoptosis	Biological Process	IDA (16044147)
GO:0006915	apoptosis	Biological Process	TAS (14555234)
GO:0006954	inflammatory response	Biological Process	IMP (10716451)
GO:0006974	response to DNA damage stimulus	Biological Process	IMP (16044147)
GO:0007050	cell cycle arrest	Biological Process	IDA (16044147)
GO:0009791	post-embryonic development	Biological Process	IMP (10716451\|15483136)
GO:0021766	hippocampus development	Biological Process	IMP (10716451)
GO:0030900	forebrain development	Biological Process	IMP (15525772)
GO:0048666	neuron development	Biological Process	IMP (12427836)