ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tnfsf4

Full Name:

tumor necrosis factor (ligand) superfamily, member 4

Alias:

Ath-1|Ath1|CD134L|OX-40L|Ox40l|TXGP1|Txgp1l|gp34

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H2.1|1 84.9 cM

Physical Location:

163325588-163348336 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7292 Symbol (Name): TNFSF4 (tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa))

Ortholog Status:

The human GeneID 7292 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009452.1	NP_033478.1	NC_000067.5 range: 163325588..163348336

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005125	cytokine activity	Molecular Function	IEA
GO:0005164	tumor necrosis factor receptor binding	Molecular Function	IPI (14635034)
GO:0005515	protein binding	Molecular Function	IPI (8765008)
GO:0008203	cholesterol metabolic process	Biological Process	IMP (3473481)
GO:0006955	immune response	Biological Process	IEA
GO:0006954	inflammatory response	Biological Process	IPI (14635034)
GO:0050710	negative regulation of cytokine secretion	Biological Process	IPI (14635034)