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Gene Information
Gene ID:22178
Symbol:Tyrp1
Full Name:tyrosinase-related protein 1
Alias:TRP-1|TRP1|Tyrp|b|brown|isa
Organism:Mus musculus (Mouse)
Chromosome:4
Genetic Location:4 C3|4 38.0 cM
Physical Location:80480133-80497621 on NC_000070.5
Gene Type:protein-coding
Human Ortholog:GeneID: 7306    Symbol (Name): TYRP1 (tyrosinase-related protein 1)
Ortholog Status:The human GeneID 7306 is not in current human dataset.
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcw2Acute Alcohol Withdrawal43838-38.7 (cM)8.82.00E-10SignificantPARC
Caws2Chronic Alcohol Withdrawal4 33-51 (cM)2.30.005SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_031202.2NP_112479.1NC_000070.5 range: 80480133..80497621
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0004497monooxygenase activityMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0042803protein homodimerization activityMolecular FunctionIDA (9918801)
GO:0016491oxidoreductase activityMolecular FunctionIEA
GO:0046982protein heterodimerization activityMolecular FunctionIDA (9918801)
GO:0005507copper ion bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (9918801)
GO:0030318melanocyte differentiationBiological ProcessIMP (2379821)
GO:0032438melanosome organization and biogenesisBiological ProcessIMP (9548375)
GO:0006582melanin metabolic processBiological ProcessIMP (9548375)
GO:0043438acetoacetic acid metabolic processBiological ProcessIMP (7665913)
GO:0043473pigmentationBiological ProcessIMP (2379821|13880466|17247639)
GO:0006583melanin biosynthetic process from tyrosineBiological ProcessTAS (9918801)
GO:0008152metabolic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:22178
MGI:
Ensembl:ENSMUSG00000005994
dbSNP:Tyrp1
AceView:Tyrp1