ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ucp1

Full Name:

uncoupling protein 1 (mitochondrial, proton carrier)

Alias:

AI385626|Slc25a7|Ucp

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 C2|8 38.0 cM

Physical Location:

85814260-85821950 on NC_000074.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7350 Symbol (Name): UCP1 (uncoupling protein 1 (mitochondrial, proton carrier))

Ortholog Status:

The human GeneID 7350 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009463.2	NP_033489.1	NC_000074.5 range: 85814260..85821950

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IDA (11940593\|14651853)
GO:0005740	mitochondrial envelope	Cellular Component	IDA (12910269)
GO:0005743	mitochondrial inner membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005215	transporter activity	Molecular Function	IEA
GO:0005488	binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12910269)
GO:0017077	oxidative phosphorylation uncoupler activity	Molecular Function	IDA (12910269)
GO:0006839	mitochondrial transport	Biological Process	IEA
GO:0006810	transport	Biological Process	IEA
GO:0050873	brown fat cell differentiation	Biological Process	IEP (15567149)