ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Adamts20

Full Name:

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20

Alias:

ADAMST-20|ADAMTS-20|Adamst20|bt

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 E3|15 44.4 cM

Physical Location:

94100593-94234688 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 80070 Symbol (Name): ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif, 20)

Ortholog Status:

The human GeneID 80070 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_177431.3	NP_803180.2	NC_000081.5 range: 94100593..94234688, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005575	cellular_component	Cellular Component	ND
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0031012	extracellular matrix	Cellular Component	IEA
GO:0004222	metalloendopeptidase activity	Molecular Function	IDA (12562771)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0008237	metallopeptidase activity	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0007229	integrin-mediated signaling pathway	Biological Process	IEA
GO:0006508	proteolysis	Biological Process	IDA (12562771)