ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Wnt1

Full Name:

wingless-related MMTV integration site 1

Alias:

Int-1|Wnt-1|sw|swaying

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 F1-F3|15 56.8 cM

Physical Location:

98620287-98624260 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7471 Symbol (Name): WNT1 (wingless-type MMTV integration site family, member 1)

Ortholog Status:

The human GeneID 7471 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_021279.4	NP_067254.1	NC_000081.5 range: 98620287..98624260

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	IEA
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (10866835\|15454084\|16126904)
GO:0005102	receptor binding	Molecular Function	TAS (9889131)
GO:0048663	neuron fate commitment	Biological Process	IMP (16339193)
GO:0042472	inner ear morphogenesis	Biological Process	IGI (15961523)
GO:0022004	midbrain-hindbrain boundary maturation during brain development	Biological Process	IMP (8555108)
GO:0021797	forebrain anterior/posterior pattern formation	Biological Process	IGI (18094027)
GO:0021536	diencephalon development	Biological Process	IGI (18094027)
GO:0016055	Wnt receptor signaling pathway	Biological Process	IDA (16207730)
GO:0009887	organ morphogenesis	Biological Process	TAS (9889131)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007267	cell-cell signaling	Biological Process	TAS (9889131)
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	TAS (9889131)
GO:0048664	neuron fate determination	Biological Process	IMP (16339193)