ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

22431

Symbol:

Wt1

Full Name:

Wilms tumor homolog

Alias:

D630046I19Rik|Wt-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 E|2 58.0 cM

Physical Location:

104966685-105013770 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7490 Symbol (Name): WT1 (Wilms tumor 1)

Ortholog Status:

The human GeneID 7490 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_144783.2	NP_659032.3	NC_000068.6 range: 104966685..105013770

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IDA (14678822)
GO:0005634	nucleus	Cellular Component	ISS (17056598)
GO:0005634	nucleus	Cellular Component	IDA (11509181\|11555636\|12151099\|14678822)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12151099\|14603255)
GO:0003700	transcription factor activity	Molecular Function	IDA (7585606\|16264195)
GO:0003690	double-stranded DNA binding	Molecular Function	IDA (7585606)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003676	nucleic acid binding	Molecular Function	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (16264195)
GO:0008584	male gonad development	Biological Process	IMP (15063178)
GO:0009888	tissue development	Biological Process	IMP (15716344)
GO:0030855	epithelial cell differentiation	Biological Process	IMP (9118800)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA
GO:0043010	camera-type eye development	Biological Process	IMP (11889045\|15716344)
GO:0007530	sex determination	Biological Process	IMP (11509181)
GO:0007281	germ cell development	Biological Process	IMP (15063178)
GO:0007049	cell cycle	Biological Process	IEA
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (12151099)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA (11889045)
GO:0006350	transcription	Biological Process	IEA
GO:0001823	mesonephros development	Biological Process	IMP (9118800)
GO:0001656	metanephros development	Biological Process	IMP (10322633\|11509181)
GO:0001570	vasculogenesis	Biological Process	IMP (16264195)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	ISS (7585606)