ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Lrp4

Full Name:

low density lipoprotein receptor-related protein 4

Alias:

6430526J12Rik|D230026E03|Megf7|mdig

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 E1|2 50.0 cM

Physical Location:

91297857-91353935 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4038 Symbol (Name): LRP4 (low density lipoprotein receptor-related protein 4)

Ortholog Status:

The human GeneID 4038 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_172668.2	NP_766256.2	NC_000068.6 range: 91297857..91353935

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	RCA (12466851)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005886	plasma membrane	Cellular Component	IDA (16263759)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	RCA (12466851)
GO:0030326	embryonic limb morphogenesis	Biological Process	IMP (16207730\|17119023)
GO:0042475	odontogenesis of dentine-containing teeth	Biological Process	IMP (17119023)
GO:0042733	embryonic digit morphogenesis	Biological Process	IMP (16517118)
GO:0043113	receptor clustering	Biological Process	IMP (17119023)
GO:0048856	anatomical structure development	Biological Process	IMP (17119023)
GO:0001822	kidney development	Biological Process	IMP (17119023)
GO:0030178	negative regulation of Wnt receptor signaling pathway	Biological Process	IDA (16207730)
GO:0009954	proximal/distal pattern formation	Biological Process	IMP (17119023)
GO:0009953	dorsal/ventral pattern formation	Biological Process	IMP (16207730\|17119023)
GO:0008104	protein localization	Biological Process	IMP (17119023)
GO:0006897	endocytosis	Biological Process	IEA
GO:0001942	hair follicle development	Biological Process	IMP (17119023)
GO:0051124	synaptic growth at neuromuscular junction	Biological Process	IMP (17119023)