ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SCAP

Full Name:

SREBF chaperone

Alias:

KIAA0199

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

3p21.31

Physical Location:

47430187-47492448 on NC_000003.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 235623 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

SCAP

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_012235.2	NP_036367.2	NC_000003.10 range: 47430187..47492448, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000139	Golgi membrane	Cellular Component	IEA
GO:0005783	endoplasmic reticulum	Cellular Component	NAS (11726962)
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA
GO:0005794	Golgi apparatus	Cellular Component	NAS (11726962)
GO:0031410	cytoplasmic vesicle	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	NAS (11726962)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0051082	unfolded protein binding	Molecular Function	NAS (11726962)
GO:0008202	steroid metabolic process	Biological Process	IEA
GO:0006994	positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response	Biological Process	IMP (11726962)
GO:0006629	lipid metabolic process	Biological Process	IEA
GO:0045541	negative regulation of cholesterol biosynthetic process	Biological Process	NAS (11969205)
GO:0045716	positive regulation of low-density lipoprotein receptor biosynthetic process	Biological Process	NAS (11726974)
GO:0008203	cholesterol metabolic process	Biological Process	IEA