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Gene Information
Gene ID:23164
Symbol:MPRIP
Full Name:myosin phosphatase Rho interacting protein
Alias:KIAA0864|M-RIP|RHOIP3|p116Rip
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17p11.2
Physical Location:16886831-17029598 on NC_000017.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S1857  16355942
Region:14355942-18355942
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_015134.2NP_055949.2NC_000017.9 range: 16886831..17029598
NM_201274.2NP_958431.2NC_000017.9 range: 16886831..17029598
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005856cytoskeletonCellular ComponentIEA
GO:0003779actin bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (17353931)
Other Database Cross Links
NCBI Entrez Gene:23164
HGNC:30321
Ensembl:ENSG00000133030
MIM:
HPRD:17591
HuGE Navigator:23164
dbSNP:MPRIP
GeneCard:MPRIP
AceView:MPRIP