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Gene Information
Gene ID:23176
Symbol:SEPT8
Full Name:septin 8
Alias:KIAA0202|SEP2
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q31
Physical Location:132114407-132141459 on NC_000005.8, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 20362 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:D86957
Fold Change:-1.5, -1.4
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001098811.1NP_001092281.1NC_000005.8 range: 132114407..132141459, complement
NM_001098812.1NP_001092282.1NC_000005.8 range: 132114407..132141459, complement
NM_001098813.1NP_001092283.1NC_000005.8 range: 132114407..132141459, complement
NM_015146.1NP_055961.1NC_000005.8 range: 132114407..132141459, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0031105septin complexCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (16767699|17353931)
GO:0005525GTP bindingMolecular FunctionIEA
GO:0007049cell cycleBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:23176
HGNC:16511
Ensembl:
MIM:608418
HPRD:
HuGE Navigator:23176
dbSNP:SEPT8
GeneCard:SEPT8
AceView:SEPT8