ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Dmn

Full Name:

desmuslin

Alias:

4930412K21Rik|AI852401|E130104F11|MGC56976|Syn|Synemin

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 C

Physical Location:

74875053-74904578 on NC_000073.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 23336 Symbol (Name): DMN (desmuslin)

Ortholog Status:

The human GeneID 23336 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AW050361
Fold Change:		1.3, 1.5, 1.6, 1.5
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005624	membrane fraction	Cellular Component	IDA (16817202)
GO:0005882	intermediate filament	Cellular Component	ISO
GO:0030018	Z disc	Cellular Component	ISO
GO:0060053	neurofilament cytoskeleton	Cellular Component	IDA (16817202)
GO:0005515	protein binding	Molecular Function	ISO
GO:0030674	protein binding, bridging	Molecular Function	ISO
GO:0008150	biological_process	Biological Process	ND