ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Helt

Full Name:

Hey-like transcription factor (zebrafish)

Alias:

A830086M02|Hesl|Mgn|megane

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 B1.1|8 27.0 cM

Physical Location:

47377400-47380024 on NC_000074.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 391723 Symbol (Name): HELT (HES/HEY-like transcription factor)

Ortholog Status:

The human GeneID 391723 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_173789.4	NP_776150.2	NC_000074.5 range: 47377400..47380024, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005667	transcription factor complex	Cellular Component	IDA (14764602)
GO:0005634	nucleus	Cellular Component	IEA
GO:0016564	transcription repressor activity	Molecular Function	IDA (14764602)
GO:0042803	protein homodimerization activity	Molecular Function	IDA (14764602)
GO:0005515	protein binding	Molecular Function	IPI (14764602)
GO:0003700	transcription factor activity	Molecular Function	IDA (14764602)
GO:0003677	DNA binding	Molecular Function	IDA (14764602)
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0030182	neuron differentiation	Biological Process	IGI (15071116)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (14764602)