ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Aloxe3

Full Name:

arachidonate lipoxygenase 3

Alias:

MGC143829|MGC143830|e-LOX-3

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B3|11 37.0 cM

Physical Location:

68939878-68962615 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 59344 Symbol (Name): ALOXE3 (arachidonate lipoxygenase 3)

Ortholog Status:

The human GeneID 59344 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore4	Alcohol-induced Loss of Righting Reflex	11		36-42 (cM)	6.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011786.1	NP_035916.1	NC_000077.5 range: 68939878..68962615

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0003824	catalytic activity	Molecular Function	ISS (10366447)
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0016165	lipoxygenase activity	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006691	leukotriene metabolic process	Biological Process	IEA
GO:0019370	leukotriene biosynthetic process	Biological Process	IEA