Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:23908
Full Name:heparan sulfate 2-O-sulfotransferase 1
Organism:Mus musculus (Mouse)
Genetic Location:3 H2
Physical Location:144094073-144233101 on NC_000069.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 9653    Symbol (Name): HS2ST1 (heparan sulfate 2-O-sulfotransferase 1)
Ortholog Status:The human GeneID 9653 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs2st1
Dataset Information
Tissue:Whole brain
Phenotype:Alcohol preference
Publication:Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (|d|) and lowest Q values.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_011828.3NP_035958.3NC_000069.5 range: 144094073..144233101, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0004394heparan sulfate 2-O-sulfotransferase activityMolecular FunctionIMP (11457822)
GO:0016740transferase activityMolecular FunctionIEA
GO:0015014heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic processBiological ProcessIMP (11457822)
GO:0030202heparin metabolic processBiological ProcessIMP (11457822)
Other Database Cross Links
NCBI Entrez Gene:23908