ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nr2e3

Full Name:

nuclear receptor subfamily 2, group E, member 3

Alias:

A930035N01Rik|PNR|RNR|rd7

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 B|9 33.5 cM

Physical Location:

59790577-59797885 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10002 Symbol (Name): NR2E3 (nuclear receptor subfamily 2, group E, member 3)

Ortholog Status:

The human GeneID 10002 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap5q	Alcohol Preference Drinking	9	25	10-35 (cM)	4.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013708.4	NP_038736.1	NC_000075.5 range: 59790577..59797885, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (15689355)
GO:0005667	transcription factor complex	Cellular Component	IDA (15689355)
GO:0016439	tRNA-pseudouridine synthase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (15689355)
GO:0005496	steroid binding	Molecular Function	IEA
GO:0004879	ligand-dependent nuclear receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0003707	steroid hormone receptor activity	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IDA (15689355)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (15689355)
GO:0045872	positive regulation of rhodopsin gene expression	Biological Process	IGI (15689355)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (15689355)
GO:0008285	negative regulation of cell proliferation	Biological Process	IMP (12407160)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0060041	retina development in camera-type eye	Biological Process	IMP (12407160)