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Gene Information
Gene ID:24248
Symbol:Cat
Full Name:catalase
Alias:CS1|Cas1|Cs-1|RATCAT01|RATCATL
Organism:Rattus norvegicus (Rat)
Chromosome:3
Genetic Location:3q32-q34
Physical Location:88654076-88686211 on NC_005102.2
Gene Type:protein-coding
Human Ortholog:GeneID: 847    Symbol (Name): CAT (catalase)
Ortholog Status:The human GeneID 847 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Cat
Fold Change:1.42
Tissue:Accumbens
Dataset Information
Name:17517326
Method:Microarray
Tissue:Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_012520.1NP_036652.1NC_005102.2 range: 88654076..88686211
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005778peroxisomal membraneCellular ComponentISS
GO:0005777peroxisomeCellular ComponentIDA
GO:0005739mitochondrionCellular ComponentISS
GO:0016684oxidoreductase activity, acting on peroxide as acceptorMolecular FunctionISS
GO:0016491oxidoreductase activityMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0005506iron ion bindingMolecular FunctionIEA
GO:0004096catalase activityMolecular FunctionIDA (3455767|15773229|15777843|15869839)
GO:0004096catalase activityMolecular FunctionIEA
GO:0004096catalase activityMolecular FunctionISS
GO:0004096catalase activityMolecular FunctionTAS (2792765)
GO:0006979response to oxidative stressBiological ProcessIEA
GO:0042744hydrogen peroxide catabolic processBiological ProcessIEA
GO:0042744hydrogen peroxide catabolic processBiological ProcessIMP (14713308)
GO:0042744hydrogen peroxide catabolic processBiological ProcessISS
GO:0000302response to reactive oxygen speciesBiological ProcessIMP (14713308)
Other Database Cross Links
NCBI Entrez Gene:24248
RGD:2279
Ensembl:ENSRNOG00000008364
dbSNP:Cat