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Gene Information
Gene ID:24259
Symbol:Chgb
Full Name:chromogranin B
Alias:MGC156676
Organism:Rattus norvegicus (Rat)
Chromosome:3
Genetic Location:3q36
Physical Location:120571735-120584873 on NC_005102.2
Gene Type:protein-coding
Human Ortholog:GeneID: 1114    Symbol (Name): CHGB (chromogranin B (secretogranin 1))
Ortholog Status:The human GeneID 1114 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Chgb
Fold Change:1.25
Tissue:Amygdala
Dataset Information
Name:17517326
Method:Microarray
Tissue:Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_012526.1NP_036658.1NC_005102.2 range: 120571735..120584873
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0030141secretory granuleCellular ComponentIDA (2641278)
GO:0005515protein bindingMolecular FunctionISS
Other Database Cross Links
NCBI Entrez Gene:24259
RGD:2339
Ensembl:ENSRNOG00000021269
dbSNP:Chgb