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Gene Information
Gene ID:24750
Symbol:RT1-N3
Full Name:RT1 class Ib gene, H2-TL-like, grc region (N3)
Organism:Rattus norvegicus (Rat)
Chromosome:20
Genetic Location:20p12
Physical Location:2806840-2810078 on NC_005119.2
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:RT1-N3
Fold Change:1.26
Tissue:Amygdala
Gene Information
Original ID1:RT1-N3
Fold Change:1.35
Tissue:Hippocampus
Dataset Information
Name:17517326
Method:Microarray
Tissue:Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001008855.1NP_001008855.1NC_005119.2 range: 2806840..2810078
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0042612MHC class I protein complexCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0005622intracellularCellular ComponentIEA
GO:0005840ribosomeCellular ComponentIEA
GO:0016787hydrolase activityMolecular FunctionIEA
GO:0008026ATP-dependent helicase activityMolecular FunctionIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0003735structural constituent of ribosomeMolecular FunctionIEA
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0006955immune responseBiological ProcessIEA
GO:0002474antigen processing and presentation of peptide antigen via MHC class IBiological ProcessIEA
GO:0019882antigen processing and presentationBiological ProcessIEA
GO:0006412translationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:24750
RGD:1598370
Ensembl:ENSRNOG00000000795
dbSNP:RT1-N3