Gene Information |
Gene ID: | | 25095 |
Symbol: | | Ampd3 |
Full Name: | | adenosine monophosphate deaminase 3 |
Organism: | | Rattus norvegicus (Rat) |
Chromosome: | | 1 |
Genetic Location: | | 1q35-q36 |
Physical Location: | | 168533491-168568290 on NC_005100.2 |
Gene Type: | | protein-coding |
Human Ortholog: | | GeneID: 272 Symbol (Name): AMPD3 (adenosine monophosphate deaminase (isoform E)) |
Ortholog Status: | | The human GeneID 272 is not in current human dataset. |
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Gene in Ethanol Study Datasets |
Gene Information | Original ID1: | | Ampd3 | Fold Change: | | 1.37 | Tissue: | | Accumbens |
| Dataset Information | Name: | | 17517326 | Method: | | Microarray | Tissue: | | Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus | Phenotype: | | Alcohol-preferring, alcohol-nonpreferring | Publication: | | Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed | Summary: | | The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change. |
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Gene Refseq Sequence Annotation |
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Gene Ontology (GO) Annotation |
GO ID | GO Term | Category | Evidence (PubMed) | |
GO:0003876 | AMP deaminase activity | Molecular Function | IDA (9291127) | |
GO:0003876 | AMP deaminase activity | Molecular Function | IEA | |
GO:0016787 | hydrolase activity | Molecular Function | IEA | |
GO:0006196 | AMP catabolic process | Biological Process | TAS (9291127) | |
GO:0009117 | nucleotide metabolic process | Biological Process | IEA | |
GO:0009168 | purine ribonucleoside monophosphate biosynthetic process | Biological Process | IEA | |
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Other Database Cross Links |
NCBI Entrez Gene: | | 25095 |
RGD: | | 2111 |
Ensembl: | | ENSRNOG00000018262 |
dbSNP: | | Ampd3 |