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Gene Information
Gene ID:25145
Symbol:Cd24
Full Name:CD24 antigen
Alias:Cd24a|MGC93641
Organism:Rattus norvegicus (Rat)
Chromosome:20
Genetic Location:20q13
Physical Location:47502358-47507657 on NC_005119.2
Gene Type:protein-coding
Human Ortholog:GeneID: 934    Symbol (Name): CD24 (CD24 molecule)
Ortholog Status:The human GeneID 934 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Cd24
Fold Change:1.32
Tissue:Amygdala
Dataset Information
Name:17517326
Method:Microarray
Tissue:Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_012752.3NP_036884.1NC_005119.2 range: 47502358..47507657
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005624membrane fractionCellular ComponentISS
GO:0009897external side of plasma membraneCellular ComponentIDA
GO:0009897external side of plasma membraneCellular ComponentISS
GO:0060170cilium membraneCellular ComponentISS
GO:0045121membrane raftCellular ComponentISS
GO:0031362anchored to external side of plasma membraneCellular ComponentIDA
GO:0005886plasma membraneCellular ComponentISS
GO:0005886plasma membraneCellular ComponentIEA
GO:0031528microvillus membraneCellular ComponentISS
GO:0046658anchored to plasma membraneCellular ComponentTAS (9004038)
GO:0031362anchored to external side of plasma membraneCellular ComponentISS
GO:0031225anchored to membraneCellular ComponentIEA
GO:0030246carbohydrate bindingMolecular FunctionISS
GO:0030246carbohydrate bindingMolecular FunctionIEA
GO:0030296protein tyrosine kinase activator activityMolecular FunctionISS
GO:0019901protein kinase bindingMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionISS
GO:0033625positive regulation of integrin activationBiological ProcessISS
GO:0033634positive regulation of cell-cell adhesion mediated by integrinBiological ProcessISS
GO:0033632regulation of cell-cell adhesion mediated by integrinBiological ProcessISS
GO:0033630positive regulation of cell adhesion mediated by integrinBiological ProcessISS
GO:0032597B cell receptor transport into membrane raftBiological ProcessISS
GO:0032913negative regulation of transforming growth factor-beta3 productionBiological ProcessISS
GO:0032600chemokine receptor transport out of membrane raftBiological ProcessISS
GO:0034107negative regulation of erythrocyte clearanceBiological ProcessISS
GO:0034109homotypic cell-cell adhesionBiological ProcessISS
GO:0034119negative regulation of erythrocyte aggregationBiological ProcessISS
GO:0050850positive regulation of calcium-mediated signalingBiological ProcessISS
GO:0050768negative regulation of neurogenesisBiological ProcessISS
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationBiological ProcessISS
GO:0048488synaptic vesicle endocytosisBiological ProcessIEA
GO:0046641positive regulation of alpha-beta T cell proliferationBiological ProcessISS
GO:0046014negative regulation of T cell homeostatic proliferationBiological ProcessISS
GO:0048488synaptic vesicle endocytosisBiological ProcessISS
GO:0045730respiratory burstBiological ProcessISS
GO:0045665negative regulation of neuron differentiationBiological ProcessISS
GO:0045577regulation of B cell differentiationBiological ProcessISS
GO:0043408regulation of MAPKKK cascadeBiological ProcessISS
GO:0043406positive regulation of MAP kinase activityBiological ProcessISS
GO:0042632cholesterol homeostasisBiological ProcessISS
GO:0042325regulation of phosphorylationBiological ProcessISS
GO:0043627response to estrogen stimulusBiological ProcessISS
GO:0042103positive regulation of T cell homeostatic proliferationBiological ProcessISS
GO:0042104positive regulation of activated T cell proliferationBiological ProcessISS
GO:0031295T cell costimulationBiological ProcessISS
GO:0007166cell surface receptor linked signal transductionBiological ProcessISS
GO:0007159leukocyte adhesionBiological ProcessISS
GO:0007157heterophilic cell adhesionBiological ProcessISS
GO:0007155cell adhesionBiological ProcessTAS (9004038)
GO:0006955immune responseBiological ProcessIEP (16380169)
GO:0006800oxygen and reactive oxygen species metabolic processBiological ProcessISS
GO:0001666response to hypoxiaBiological ProcessISS
GO:0002904positive regulation of B cell apoptosisBiological ProcessISS
GO:0002863positive regulation of inflammatory response to antigenic stimulusBiological ProcessISS
GO:0002842positive regulation of T cell mediated immune response to tumor cellBiological ProcessISS
GO:0002523leukocyte migration during inflammatory responseBiological ProcessISS
GO:0002329pre-B cell differentiationBiological ProcessISS
GO:0002237response to molecule of bacterial originBiological ProcessISS
GO:0001959regulation of cytokine and chemokine mediated signaling pathwayBiological ProcessISS
GO:0007204elevation of cytosolic calcium ion concentrationBiological ProcessISS
GO:0007267cell-cell signalingBiological ProcessNAS (9004038)
GO:0007267cell-cell signalingBiological ProcessTAS (9004038)
GO:0031175neurite developmentBiological ProcessISS
GO:0030889negative regulation of B cell proliferationBiological ProcessISS
GO:0030262apoptotic nuclear changesBiological ProcessISS
GO:0030154cell differentiationBiological ProcessIEA
GO:0022409positive regulation of cell-cell adhesionBiological ProcessISS
GO:0022407regulation of cell-cell adhesionBiological ProcessISS
GO:0016477cell migrationBiological ProcessISS
GO:0016337cell-cell adhesionBiological ProcessNAS (9004038)
GO:0008637apoptotic mitochondrial changesBiological ProcessISS
GO:0008624induction of apoptosis by extracellular signalsBiological ProcessISS
GO:0007406negative regulation of neuroblast proliferationBiological ProcessISS
GO:0007275multicellular organismal developmentBiological ProcessIEA
GO:0007274neuromuscular synaptic transmissionBiological ProcessISS
GO:0007274neuromuscular synaptic transmissionBiological ProcessIEA
GO:0001775cell activationBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:25145
RGD:2298
Ensembl:ENSRNOG00000000321
dbSNP:Cd24