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Gene Information
Gene ID:256933
Symbol:NPB
Full Name:neuropeptide B
Alias:PPL7|PPNPB
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17q25.3
Physical Location:77453445-77453915 on NC_000017.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:NPB
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S928  77846128
Region:75846128-78774742
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_148896.2NP_683694.1NC_000017.9 range: 77453445..77453915
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIPI (12118011|12401809)
GO:0007218neuropeptide signaling pathwayBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:256933
HGNC:30099
Ensembl:ENSG00000183979
MIM:607996
HPRD:16267
HuGE Navigator:256933
dbSNP:NPB
GeneCard:NPB
AceView:NPB