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Gene Information
Gene ID:25843
Symbol:MOBKL3
Full Name:MOB1, Mps One Binder kinase activator-like 3 (yeast)
Alias:2C4D|CGI-95|MGC12264|MOB1|MOB3|PREI3
Organism:Homo sapiens (Human)
Chromosome:2
Genetic Location:2q33.1
Physical Location:198088564-198125759 on NC_000002.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D2S117  195326948
Region:195326948-216757195
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001100819.1NP_001094289.1NC_000002.10 range: 198088564..198125759
NM_015387.3NP_056202.2NC_000002.10 range: 198088564..198125759
NM_199482.2NP_955776.1NC_000002.10 range: 198088564..198125759
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (17353931)
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006810transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:25843
HGNC:17261
Ensembl:ENSG00000115540
MIM:609361
HPRD:10165
HuGE Navigator:25843
dbSNP:MOBKL3
GeneCard:MOBKL3
AceView:MOBKL3