ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

26423

Symbol:

Nr5a1

Full Name:

nuclear receptor subfamily 5, group A, member 1

Alias:

Ad4BP|ELP|ELP-3|Ftz-F1|Ftzf1|MGC124277|MGC124278|SF-1|SF1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 B|2 23.5 cM

Physical Location:

38548179-38570061 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2516 Symbol (Name): NR5A1 (nuclear receptor subfamily 5, group A, member 1)

Ortholog Status:

The human GeneID 2516 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcp1	Alcohol Preference Drinking	2	28	19-35 (cM)	5.3		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_139051.3	NP_620639.1	NC_000068.6 range: 38548179..38570061, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (10848616)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0008289	lipid binding	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12651892\|12730328\|12732652)
GO:0004879	ligand-dependent nuclear receptor activity	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IDA (12730328\|14726490\|15590666)
GO:0016563	transcription activator activity	Molecular Function	IDA (12730328)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0003707	steroid hormone receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (10446902\|12732652\|15590666)
GO:0030325	adrenal gland development	Biological Process	IGI (11796523)
GO:0030154	cell differentiation	Biological Process	IGI (15829514)
GO:0030325	adrenal gland development	Biological Process	IMP (11796523\|16176945)
GO:0009888	tissue development	Biological Process	IMP (16176945)
GO:0008584	male gonad development	Biological Process	IMP (15118069)
GO:0001553	luteinization	Biological Process	IMP (15118069)
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (12730328\|12861022)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA (12651892)
GO:0006350	transcription	Biological Process	IEA
GO:0051457	maintenance of protein localization in nucleus	Biological Process	IDA (12610109)