ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nr5a2

Full Name:

nuclear receptor subfamily 5, group A, member 2

Alias:

AU020803|D1Ertd308e|Ftf|LRH-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 E4|1 78.0 cM

Physical Location:

138740852-138857024 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2494 Symbol (Name): NR5A2 (nuclear receptor subfamily 5, group A, member 2)

Ortholog Status:

The human GeneID 2494 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_030676.1	NP_109601.1	NC_000067.5 range: 138740852..138857024, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IDA (15014077\|16912278)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0008289	lipid binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0004879	ligand-dependent nuclear receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0003707	steroid hormone receptor activity	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0008206	bile acid metabolic process	Biological Process	IMP (15014077)
GO:0042632	cholesterol homeostasis	Biological Process	IMP (15014077)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA