ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

GCNT2

Full Name:

glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)

Alias:

CCAT|GCNT2C|GCNT5|IGNT|II|MGC163396|NACGT1|NAGCT1|ULG3|bA360O19.2|bA421M1.1

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

6p24.2

Physical Location:

10636696-10737586 on NC_000006.10

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 306860 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D6S470

10133701

Region:		8133701-12133701
Phenotype:		Alcoholism phenotype along with age, gender, and P300 or constraint
Name:		15211641
Method:		Linkage
Publication:		Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:		A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000139	Golgi membrane	Cellular Component	IEA
GO:0005624	membrane fraction	Cellular Component	TAS (8449405)
GO:0005794	Golgi apparatus	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0008375	acetylglucosaminyltransferase activity	Molecular Function	IEA
GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	Molecular Function	TAS (8449405)
GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	Molecular Function	IEA
GO:0016757	transferase activity, transferring glycosyl groups	Molecular Function	IEA
GO:0007275	multicellular organismal development	Biological Process	TAS (9134435)
GO:0006493	protein amino acid O-linked glycosylation	Biological Process	NR
GO:0006024	glycosaminoglycan biosynthetic process	Biological Process	TAS (8449405)