ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Exo1

Full Name:

exonuclease 1

Alias:

5730442G03Rik|Msa

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H4|1 97.0 cM

Physical Location:

177810928-177839423 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9156 Symbol (Name): EXO1 (exonuclease 1)

Ortholog Status:

The human GeneID 9156 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_012012.4	NP_036142.2	NC_000067.5 range: 177810928..177839423

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0008409	5'-3' exonuclease activity	Molecular Function	ISS (10497278)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0043566	structure-specific DNA binding	Molecular Function	IDA (14716311)
GO:0004527	exonuclease activity	Molecular Function	IEA
GO:0004519	endonuclease activity	Molecular Function	IEA
GO:0004518	nuclease activity	Molecular Function	IEA
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0016446	somatic hypermutation of immunoglobulin genes	Biological Process	IMP (14716311)
GO:0002455	humoral immune response mediated by circulating immunoglobulin	Biological Process	IMP (14716311)
GO:0007126	meiosis	Biological Process	IEA
GO:0006974	response to DNA damage stimulus	Biological Process	IEA
GO:0006955	immune response	Biological Process	IEA
GO:0006281	DNA repair	Biological Process	IEA
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	Biological Process	ISS (10497278)
GO:0045190	isotype switching	Biological Process	IMP (14716311)