ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Gcat

Full Name:

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

Alias:

AI526977|Kbl

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 E1|15 46.6 cM

Physical Location:

78861349-78868783 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 23464 Symbol (Name): GCAT (glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase))

Ortholog Status:

The human GeneID 23464 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013847.3	NP_038875.2	NC_000081.5 range: 78861349..78868783

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0005743	mitochondrial inner membrane	Cellular Component	IDA (12865426)
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0016874	ligase activity	Molecular Function	IEA
GO:0016769	transferase activity, transferring nitrogenous groups	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0008890	glycine C-acetyltransferase activity	Molecular Function	IEA
GO:0008415	acyltransferase activity	Molecular Function	IEA
GO:0030170	pyridoxal phosphate binding	Molecular Function	IEA
GO:0009058	biosynthetic process	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA