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Gene Information
Gene ID:27040
Symbol:LAT
Full Name:linker for activation of T cells
Alias:LAT1|pp36
Organism:Homo sapiens (Human)
Chromosome:16
Genetic Location:16p11.2
Physical Location:28903647-28909604 on NC_000016.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:LAT
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001014987.1NP_001014987.1NC_000016.8 range: 28903647..28909604
NM_001014988.1NP_001014988.1NC_000016.8 range: 28903647..28909604
NM_001014989.1NP_001014989.1NC_000016.8 range: 28903647..28909604
NM_014387.3NP_055202.1NC_000016.8 range: 28903647..28909604
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0001772immunological synapseCellular ComponentIDA (12646565)
GO:0005886plasma membraneCellular ComponentEXP (11048639|11607830|17652306)
GO:0005886plasma membraneCellular ComponentIEA
GO:0045121membrane raftCellular ComponentTAS (14722116)
GO:0016021integral to membraneCellular ComponentIDA (12646565)
GO:0005070SH3/SH2 adaptor activityMolecular FunctionIDA (9489702)
GO:0005515protein bindingMolecular FunctionIPI (16938345)
GO:0043303mast cell degranulationBiological ProcessIEA
GO:0019722calcium-mediated signalingBiological ProcessIMP (12646565)
GO:0007265Ras protein signal transductionBiological ProcessIMP (12646565)
GO:0007242intracellular signaling cascadeBiological ProcessIDA (12646565)
GO:0007229integrin-mediated signaling pathwayBiological ProcessIDA (15100278)
GO:0006955immune responseBiological ProcessIDA (15100278)
GO:0050863regulation of T cell activationBiological ProcessIMP (12646565)
Other Database Cross Links
NCBI Entrez Gene:27040
HGNC:18874
Ensembl:ENSG00000169682
MIM:602354
HPRD:03832
HuGE Navigator:27040
dbSNP:LAT
GeneCard:LAT
AceView:LAT