| Gene Information |
| Gene ID: | | 27040 |
| Symbol: | | LAT |
| Full Name: | | linker for activation of T cells |
| Alias: | | LAT1|pp36 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 16 |
| Genetic Location: | | 16p11.2 |
| Physical Location: | | 28903647-28909604 on NC_000016.8 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0001772 | immunological synapse | Cellular Component | IDA (12646565) | |
| GO:0005886 | plasma membrane | Cellular Component | EXP (11048639|11607830|17652306) | |
| GO:0005886 | plasma membrane | Cellular Component | IEA | |
| GO:0045121 | membrane raft | Cellular Component | TAS (14722116) | |
| GO:0016021 | integral to membrane | Cellular Component | IDA (12646565) | |
| GO:0005070 | SH3/SH2 adaptor activity | Molecular Function | IDA (9489702) | |
| GO:0005515 | protein binding | Molecular Function | IPI (16938345) | |
| GO:0043303 | mast cell degranulation | Biological Process | IEA | |
| GO:0019722 | calcium-mediated signaling | Biological Process | IMP (12646565) | |
| GO:0007265 | Ras protein signal transduction | Biological Process | IMP (12646565) | |
| GO:0007242 | intracellular signaling cascade | Biological Process | IDA (12646565) | |
| GO:0007229 | integrin-mediated signaling pathway | Biological Process | IDA (15100278) | |
| GO:0006955 | immune response | Biological Process | IDA (15100278) | |
| GO:0050863 | regulation of T cell activation | Biological Process | IMP (12646565) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 27040 |
| HGNC: | | 18874 |
| Ensembl: | | ENSG00000169682 |
| MIM: | | 602354 |
| HPRD: | | 03832 |
| HuGE Navigator: | | 27040 |
| dbSNP: | | LAT |
| GeneCard: | | LAT |
| AceView: | | LAT |
