ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Atp1a4

Full Name:

ATPase, Na+/K+ transporting, alpha 4 polypeptide

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H3|1 94.0 cM

Gene Type:

protein-coding

Human Ortholog:

GeneID: 480 Symbol (Name): ATP1A4 (ATPase, Na+/K+ transporting, alpha 4 polypeptide)

Ortholog Status:

The human GeneID 480 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw1	Acute Alcohol Withdrawal	1	96	172.3-176.5 (Mb)	5.6	3.00E-07	Significant	PARC
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0015077	monovalent inorganic cation transmembrane transporter activity	Molecular Function	IEA
GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Molecular Function	IEA
GO:0030955	potassium ion binding	Molecular Function	IEA
GO:0031402	sodium ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0005391	sodium:potassium-exchanging ATPase activity	Molecular Function	ISO
GO:0005524	ATP binding	Molecular Function	IEA
GO:0006814	sodium ion transport	Biological Process	IEA
GO:0006810	transport	Biological Process	IEA
GO:0006811	ion transport	Biological Process	IEA
GO:0015672	monovalent inorganic cation transport	Biological Process	IEA
GO:0006812	cation transport	Biological Process	IEA
GO:0006813	potassium ion transport	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA