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Gene Information
Gene ID:27239
Symbol:GPR162
Full Name:G protein-coupled receptor 162
Alias:A-2|GRCA
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12p13
Physical Location:6801223-6806843 on NC_000012.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D12S99  5434815
Region:3434815-7434815
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_014449.1NP_055264.1NC_000012.10 range: 6801223..6806843
NM_019858.1NP_062832.1NC_000012.10 range: 6801223..6806843
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0001584rhodopsin-like receptor activityMolecular FunctionIEA
GO:0004872receptor activityMolecular FunctionIEA
GO:0007165signal transductionBiological ProcessIEA
GO:0007186G-protein coupled receptor protein signaling pathwayBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:27239
HGNC:16693
Ensembl:ENSG00000110811
MIM:
HPRD:13608
HuGE Navigator:27239
dbSNP:GPR162
GeneCard:GPR162
AceView:GPR162