ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

UTP20

Full Name:

UTP20, small subunit (SSU) processome component, homolog (yeast)

Alias:

DRIM

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

12q23

Physical Location:

100198035-100304527 on NC_000012.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D12S346

98052454

Region:		98052454-102788867
Phenotype:		Alcoholism phenotype along with age, gender, and P300 or constraint
Name:		15211641
Method:		Linkage
Publication:		Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:		A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_014503.2	NP_055318.2	NC_000012.10 range: 100198035..100304527

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005732	small nucleolar ribonucleoprotein complex	Cellular Component	ISS (15590835)
GO:0005515	protein binding	Molecular Function	IPI (16053918)
GO:0008285	negative regulation of cell proliferation	Biological Process	TAS (9673349)