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Gene Information
Gene ID:27429
Symbol:HTRA2
Full Name:HtrA serine peptidase 2
Alias:OMI|PARK13|PRSS25
Organism:Homo sapiens (Human)
Chromosome:2
Genetic Location:2p12
Physical Location:74610039-74614190 on NC_000002.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:HTRA2
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_013247.4NP_037379.1NC_000002.10 range: 74610039..74614190
NM_145074.2NP_659540.1NC_000002.10 range: 74610039..74614190
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentTAS (10971580)
GO:0005739mitochondrionCellular ComponentIEA
GO:0005758mitochondrial intermembrane spaceCellular ComponentIDA (15044455)
GO:0005783endoplasmic reticulumCellular ComponentNAS (10995577)
GO:0005789endoplasmic reticulum membraneCellular ComponentTAS (10644717)
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0004252serine-type endopeptidase activityMolecular FunctionTAS (10873535)
GO:0051082unfolded protein bindingMolecular FunctionNAS (10644717)
GO:0006950response to stressBiological ProcessTAS (10971580)
GO:0006915apoptosisBiological ProcessIEA
GO:0006508proteolysisBiological ProcessTAS (10873535)
Other Database Cross Links
NCBI Entrez Gene:27429
HGNC:14348
Ensembl:ENSG00000115317
MIM:606441
HPRD:05919
HuGE Navigator:27429
dbSNP:HTRA2
GeneCard:HTRA2
AceView:HTRA2