ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Slco1a4

Full Name:

solute carrier organic anion transporter family, member 1a4

Alias:

AI785519|Oatp2|Slc21a5

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

6 G2

Physical Location:

141753960-141804691 on NC_000072.5, complement

Gene Type:

protein-coding

Human Ortholog:

This gene has no human ortholog.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AI843160
Fold Change:		-2.0, -2.1, -3.0, -2
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_030687.1	NP_109612.1	NC_000072.5 range: 141753960..141804691, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005624	membrane fraction	Cellular Component	IDA (11279518)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005215	transporter activity	Molecular Function	IEA
GO:0008514	organic anion transmembrane transporter activity	Molecular Function	IDA (12101011)
GO:0006810	transport	Biological Process	IEA
GO:0006811	ion transport	Biological Process	IEA
GO:0006820	anion transport	Biological Process	IDA (12101011)