ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

283

Symbol:

ANG

Full Name:

angiogenin, ribonuclease, RNase A family, 5

Alias:

ALS9|MGC22466|MGC71966|RNASE4|RNASE5

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

14q11.1-q11.2

Physical Location:

20222175-20232184 on NC_000014.7

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ANG

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001097577.1	NP_001091046.1	NC_000014.7 range: 20222175..20232184
NM_001145.3	NP_001136.1	NC_000014.7 range: 20222175..20232184

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (10649442\|15735021)
GO:0005615	extracellular space	Cellular Component	IDA (3663649\|16461950\|16490744)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005730	nucleolus	Cellular Component	ISS
GO:0032311	angiogenin-PRI complex	Cellular Component	IPI (3470787)
GO:0043025	cell soma	Cellular Component	ISS
GO:0030426	growth cone	Cellular Component	ISS
GO:0005605	basal lamina	Cellular Component	IDA (15166501)
GO:0005507	copper ion binding	Molecular Function	IDA (9245697)
GO:0005102	receptor binding	Molecular Function	IDA (9122172)
GO:0003779	actin binding	Molecular Function	IDA (7679494\|11782452)
GO:0008201	heparin binding	Molecular Function	IDA (10103013)
GO:0019843	rRNA binding	Molecular Function	TAS (2457905)
GO:0004540	ribonuclease activity	Molecular Function	IDA (2424496\|2730651)
GO:0004522	pancreatic ribonuclease activity	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0042277	peptide binding	Molecular Function	IDA (11782452)
GO:0003676	nucleic acid binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IC (10649442)
GO:0004519	endonuclease activity	Molecular Function	IEA
GO:0004519	endonuclease activity	Molecular Function	TAS (10103013)
GO:0032431	activation of phospholipase A2	Biological Process	IMP (2646638)
GO:0017148	negative regulation of translation	Biological Process	IEA
GO:0050714	positive regulation of protein secretion	Biological Process	ISS
GO:0030041	actin filament polymerization	Biological Process	ISS
GO:0050714	positive regulation of protein secretion	Biological Process	IDA (2646638)
GO:0030154	cell differentiation	Biological Process	IEA
GO:0048662	negative regulation of smooth muscle cell proliferation	Biological Process	IDA (10103013)
GO:0032148	activation of protein kinase B activity	Biological Process	IMP (17125737)
GO:0042327	positive regulation of phosphorylation	Biological Process	IDA (17125737)
GO:0042592	homeostatic process	Biological Process	NAS (15166501)
GO:0016477	cell migration	Biological Process	IMP (17125737)
GO:0001541	ovarian follicle development	Biological Process	NAS (12770725)
GO:0001556	oocyte maturation	Biological Process	NAS (11438326)
GO:0001666	response to hypoxia	Biological Process	IDA (10999833\|15979542\|16490744)
GO:0001666	response to hypoxia	Biological Process	NAS (15776477)
GO:0001890	placenta development	Biological Process	NAS (11984825)
GO:0001938	positive regulation of endothelial cell proliferation	Biological Process	IDA (9122172\|9707554)
GO:0001525	angiogenesis	Biological Process	IMP (2479414\|17125737)
GO:0006651	diacylglycerol biosynthetic process	Biological Process	IDA (2457905)
GO:0007154	cell communication	Biological Process	NAS (10103013)
GO:0007202	activation of phospholipase C activity	Biological Process	IMP (2457905)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0009303	rRNA transcription	Biological Process	IMP (15735021)
GO:0009725	response to hormone stimulus	Biological Process	IDA (10999833)
GO:0001525	angiogenesis	Biological Process	TAS (16567967)